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KMID : 0613320060120010001
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Journal of the Korean Bone and Joint Tumor Soceity
2006 Volume.12 No. 1 p.1 ~ p.8
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Clinical Outcome of Stage IIB Osteosarcomas in Long Bones
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Chung Yang-Guk
Rhee Seung-Koo
Kim Hyoung-Min
Park Won-Jong
Lee An-Hi
Park Jeong-Mi
Kang Yong-Koo
Choi Kwang-Cheon
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Abstract
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Purpose: To analyze the clinical outcome of stage IIB osteosarcomas arisen in the long bones.
Materials and Methods: Since February 1993, 58 Enneking stage IIB osteosarcomas arisen in long bones were managed and followed at least one year at our four university hospitals. There were 48 wide resections, 2 marginal resections and 8 amputations. The mean follow up period was 4.1years (up to 12.2years). Local recurrence, distant metastasis, complication, survival rate, and oncologic and functional results were evaluated.
Results: At the last follow up, 35 patients were CDF, 9 were NED, 5 were AWD, 7 were DOD and the remained 2 died with unrelated disease. Eight local recurrences (13.8%) and 18 distant metastases (31.0%) were occurred. Nine infections were developed after 48 reconstructions (18.8%). Overall functional outcome was 24.3 (81.%). The 5 year overall survival rate was 84.6% and the continuous disease-free survival rate was 68.7% at 5 years and 42.3% at 10 years.
Conclusion: Forty-six of 58 stage IIB osteosarcomas arisen in long bones (79.3%) showed CDF or NED at an average 4.1 year follow up. Overall 5-year survival rate was 84.6% and overall functional outcome score was 24.3, which were comparable to those of other studies.
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KEYWORD
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Long bone, Osteosarcoma, Stage IIB, Clinical outcome
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